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8): Superior glycemic control (fasting glucose, HOMA-IR) and triglyceride reduction vs dhBBR at 50 mg/kg in db/db mice [221]

Two authors assessed the risk of bias for each study through five aspects: random sequence generation, allocation concealment, blinding, incomplete outcome data and selective reporting

There are no ongoing or planned clinical studies addressing the role of tirzepatide in CKD

Another meta-analysis including children ages 6-17 with obesity, type 2 diabetes, or prediabetes found that GLP-1s significantly reduced A1C and weight compared to placebo

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High blood sugar, insulin levels, and inflammation from obesity can cause cancer