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[DOI] [PMC free article] [PubMed] [Google Scholar] 90.Neeland I.J., Linge J., Birkenfeld A.L

J Diabetes Res 2019(9426014)

Consequently, other strategies for oral administration have been tested and developed, including (but not limited to) coadministration with enzyme inhibitors, structural modifications [cyclization, PEGylation, fatty acid conjugates of polypeptides (lipidization), fusing therapeutic proteins to cobalamin (vitamin B 12 )], and the use of delivery carriers or absorption enhancers

It acts directly on the satiety centers of the brain (hypothalamus), decreasing the desire to eat

These effects are generally mild to moderate and tend to improve over time, especially when dosing is adjusted gradually

This hormone helps control blood sugar, makes you feel full faster, and slows down how quickly food moves through your stomach