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354 GLP-1RAs and musculoskeletal health GLP-1RAs and bone The quality of bone depends on bone metabolism, and the main factors affecting bone metabolism include osteoclasts, osteoblasts, and calcitonin

Disturbance of insulin signaling in diabetic patients might lead to the abnormal expression of Syn, damage to mitochondrial function, increase in mitochondrial oxidative stress, and down-regulation of the PI3K/AKT pathway, which in turn could promote the occurrence and development of PD (62)

10.2337/db11-1506 [DOI] [PMC free article] [PubMed] [Google Scholar] 92.Baturcam E, Abubaker J, Tiss A, Abu-Farha M, Khadir A, Al-Ghimlas F, et al

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Sustained GCG action has been associated with enhanced insulin-stimulated glucose disposal in lean and obese mice [44]

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