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Disclosures: Sadiya S

Most people are familiar with GLP-1 medications such as Wegovy and Ozempic

And one of the most important nutrients to consume, especially while youre losing weight, is protein

Short-acting and long-acting GLP-1 receptor agonists improved blood glycemic control and lowered body weight in individuals with T2DM

A GP, pharmacist, or specialist clinician can: Review your current medication list for potential interactions, particularly with diabetes medications, anticoagulants, thyroid treatments, and hormonal contraceptives Assess your nutritional status and advise on appropriate supplementation only where deficiencies are confirmed Monitor for adverse effects such as hypoglycaemia, gastrointestinal disturbance, or unexpected changes in blood pressure or heart rate Refer you to appropriate NHS services , including Tier 3 weight management programmes, if you are seeking structured support for obesity Discuss contraception and family planning , as retatrutide should not be used during pregnancy or breastfeeding

NICE recommends disease-modifying antirheumatic drugs (DMARDs) such as methotrexate as first-line treatment, with biologic therapies (TNF inhibitors, IL-6 inhibitors) or JAK inhibitors for patients with inadequate response