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Partly through these actions, GLP-1 receptor agonism was shown to reduce cardiovascular disease (CVD) in people with T2D with previous CVD or at high-risk thereof
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Jardiance (empagliflozin) 38% CV death reduction vs Mounjaro (tirzepatide) 21% weight loss (EMPA-REG vs SURPASS)
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Metformin is a first-line drug for treating type 2 diabetes associated with AMPK activation
