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The authors connect this to something known as the rate hypothesis in addiction research: the faster a substance hits the brain, the stronger and more rewarding it feels

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Una reciente revisin narrativa analiza los efectos del agonismo del receptor de incretina particularmente de los agonistas del receptor del pptido similar al glucagn tipo 1 (GLP-1RA) y de los agonistas duales de los receptores GLP-1 y GIP (GLP-1/GIPRA) sobre la masa libre de grasa (MLG) y la aptitud cardiorrespiratoria

Which means the next phase is beginning

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June 6, 2025 A large retrospective review of more than 100,000 patients found the use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in moderate peripheral artery disease (PAD) is associated with a decreased rate of cardiovascular events, major limb events and inpatient admissions