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Concerns have also been expressed regarding a possible link between GLP-1 receptor agonists and medullary thyroid cancer [161]

Constipation and other GI side effects are consistently worse when doses are escalated quickly

Other studies have reported that a reduction in hippocampal neurogenesis leads to an increase in anxiety symptoms and the onset of depression (Moylan et al., 2013

S., Liu, R., Zhao, Y., & ACHIEVE-3 Investigators (2026)

ACKNOWLEDGMENTS This work wassupported by the National Research Foundation of Korea (NRF) grant funded by the Ministry of Science and ICT (NRF-2020R1F1A1069257) and the Ministry of Education, Science and Technology (NRF-2019R1A6A1A03031807)

Wang W, Mei A, Qian H, et al
