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Glucagon-Like Peptide-1 (GLP-1) agonist medications, like semaglutide, are injectable or oral drugs that mimic the natural GLP-1 hormone, which helps regulate insulin levels

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Cohorts who were unresponsive to previous strategies like portion control may be responding to the new GLP 1 drugs.

Among T2DM patients on antipsychotics, more patients in the combination group achieved weight loss5% within the study period compared to metformin monotherapy