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Pharmacogenetics of glucagon-like peptide-1 agonists for the treatment of type 2 diabetes mellitus

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In the following sections, we will review these CVOTs on incretin-based therapies in detail

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doi: 10.1016/j.jacbts.2018.09.004 126 RizzoMNikolicDPattiAMManninaCMontaltoGMcAdamsBSet al

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GLP-1 RAs in MASH: Mechanisms of Action Although primarily used for the management diabetes and obesity, recent research indicates that GLP-1 RAs may also offer benefits to liver health

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Glucagonlike peptide1, but not glucosedependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas

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Insulin analogues differently activate insulin receptor isoforms and post-receptor signalling

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