glp-1 and breastfeeding Breastfeeding: Safety Evidence and Clinical Consider... – PlexusDx GLP-1 meds like Ozempic® and

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doi: 10.2337/db17-1212

In a review of clinical trials, the combination of combined oral contraceptive pills (COCPs) with either a GLP-1RA or tirzepatide (GLP-1 and Glucose-dependent insulinotropic polypeptide (GIP) receptors agonist) did not affect the efficacy of contraceptive drugs, even though GLP-1RAs can decrease the absorption of the concomitantly administered drug through their gastric delaying effect

Conservative management strategies include: Optimize gastrointestinal function: Address constipation proactively with adequate hydration (individualized to the patient's cardiovascular and renal status), dietary fiber supplementation, and when necessary, osmotic laxatives such as polyethylene glycol

The experiments revealed that gastric secretion was stimulated by the consumption of mixed meals, meats and milk, but was inhibited by fatty food and possibly aided by an adaptive immune response (Ivy, Lim, McCarthy