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GLP-1, a hormone secreted by the intestines, lowers blood glucose and promotes weight loss through multiple mechanisms: it enhances insulin secretion in a glucose concentration-dependent manner, suppresses glucagon release, delays gastric emptying, and reduces food intake via central appetite suppression
in patients with knee osteoarthritis and type 2 diabetes if treatment is sustained for a sufficient period, according to data.The researchers, who published their findings in the Annals of the Rheumatic Diseases, added that the result may be mediated by weight loss.
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GLP-1 is a synthetic peptide analog of glucagon-like peptide-1 that is widely studied in biochemical and physiological research
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