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Description
The novel peptide is biased towards GLP-1R agonism versus GCGR with a 3-4 fold reduced potency at the GLP-1R compared to native GLP-1 and around an 8-fold reduced potency at the GCGR compared to native glucagon
PMID 39779270 FDA-approved prescribing information for Ozempic (semaglutide)
Kristin Louden: Well, recently, the FDA issued warnings about compounded GLP-1 manufacturers
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