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While ertugliflozin did not outperform placebo for MACE, it significantly reduced hospitalizations for HF by 30% (59)
Figure 1: Incidence Rate of all GLP-1 Agonists
Similarly, when abliglutide was used in patients with known HFrEF, no improvement was noted in LVEF (left ventricular ejection fraction) [28]
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In a pilot study, treatment with liraglutide increased glucose utilisation in the brain as detected by (18)F-fluorodeoxyglucose( 18 FDG)-positron emission tomographyPET (PET) scans (66)
