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Most side effects are mild to moderate and may include temporary nausea or gastrointestinal discomfort, particularly during dose escalation

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Key Research Findings: A recent Penn Medicine study found no increased risk of depressive symptoms or suicidal thoughts in people without pre-existing mental health conditions [2] Only 2.8% of semaglutide-treated participants required mental health evaluation for depression, compared to 4.1% in the placebo group The European Medicines Agency is actively investigating the potential link between these medications and thoughts of self-harm While current evidence doesn't show a definitive cause-and-effect relationship between Ozempic and depression [3] , healthcare providers emphasize the importance of monitoring patients for behavioral changes