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A 2023 meta-analysis showed average weight loss of 1015% over 68 weeks for weight-loss indication and improved glycemic control with cardiovascular benefits in diabetic populations, supporting medical necessity arguments
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Higher preoperative BMI, radical tumor resection, larger preoperative tumor size, hypothalamic tumor invasion, adamantinomatous subtype, and familial predisposition to obesity are cited as factors that increase the risk of HO [49, 52, 53]

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