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N Engl J Med 2017;377:723e32

Prentki, M., Corkey, B

Standard Community Cycle Structure Self-reported community protocols most commonly describe an 8-on / 8-off structure: 8 weeks dosing, then an 8-week off window

Many patients taking GLP-1 receptor agonists for diabetes or weight management report improvements in joint pain, prompting questions about whether these medications directly address musculoskeletal symptoms

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A third SGLT-2 inhibitor, ertugliflozin, was deleted from the Australian market in mid-2023