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Once in circulation, it activates two receptors that the gut normally talks to after a meal: GIP and GLP-1

Key points: Understanding Mounjaro headaches Headaches affect 5-10% of Mounjaro users in the UK Most headaches are mild to moderate and temporary Headaches typically peak after starting treatment or increasing dose Over-the-counter pain relief like paracetamol is usually effective Headaches rarely lead to patients stopping Mounjaro treatment Why Mounjaro might cause headaches Headaches while taking Mounjaro typically come from several indirect factors rather than the medication directly affecting the brain

In some cases, surgical removal of the gallbladder (cholecystectomy) is required