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The primary objective was to determine whether dapagliflozin 10 mg reduces the incidence of the composite endpoint of 50% sustained decline in eGFR, progression to end-stage kidney disease (ESKD) (defined as sustained eGFR 40% and evidence of structural heart disease to determine whether dapagliflozin reduces the risk of cardiovascular death, hospitalization for heart failure or urgent heart failure visits

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Biopsies were taken from the terminal ilium cecum, transverse colon, sigmoid colon, and rectum

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Hypoglycaemia: Risk is low when used without insulin or sulphonylureas, but men with type 2 diabetes on combination therapy should monitor blood glucose carefully

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