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That distinction changes everything about how you dose, when you start, and what to expect during those critical first weeks

They arrive early, peak during dose escalation, and gradually taper as your body adapts to the medications core mechanism: slowing the rate at which food leaves your stomach

Phase 2 data showed that participants with a BMI of 30 to 35 lost the highest percentage (26.8%), while those with BMI over 40 lost 21.3% but often more in absolute pounds

However, its clinical usefulness remains uncertain

The 4 mg starting dose nearly doubled gastrointestinal side effects compared to 2 mg

Brew fresh ginger slices in hot water for a tea that both soothes the stomach and moistens the mouth