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Why Lilly Has Mounjaro and Zepbound: Same Drug, Different FDA Claims Mounjaro was approved by the FDA for the treatment of type 2 diabetes in 2022, following trials that demonstrated strong effects on glycemic control

Extended-release niacin formulations may cause less glucose elevation than immediate-release products but carry a higher risk of hepatotoxicity

This is theoretical rather than proven in controlled trials specifically for tirzepatide microdosing

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Severe nausea that does not resolve within the first 48 hours after injection is the most common indicator