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So then taking a GLP-1 for the rest of their life may not be something that they want to do. If a patient wants a one-time treatment, surgery is the best approach because you get it once and the results last for at least a decade, Chhabra adds

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Lancet Diabetes Endocrinol 7:776785

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Since mitochondria are highly compartmentalized organelles requiring specific transporters for the movement of metabolites and molecules, the transportation of endogenously expressed MOTS-c within organelles by transporters such as SLC25 family and between cells or tissues require further investigation

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