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Samples with PPIB ISH scores of 2 (noted as positive) and dapB ISH scores of 0 (noted as negative) were considered to have adequate tissue viability, and GIPR and GLP-1R mRNA ISH were evaluated

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GLP-1 RAs have also been shown to positively influence gut barrier integrity and immune function, potentially reducing chronic inflammation and supporting overall physiological function without measurable changes in biomarkers such as DNA methylation, telomere length, or cellular senescence

10.1210/en.2011-1443 3 BaisleyS

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