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The specific investigations may vary slightly depending on individual patient factors, but the following tests form the core pre-treatment assessment: HbA1c (Glycated Haemoglobin): This test measures average blood glucose levels over the preceding 812 weeks and is the gold standard for assessing glycaemic control

For patients who might benefit from pharmacotherapy, GLP-1 receptor agonists like Wegovy are increasingly favoured due to their robust evidence base, including cardiovascular safety data and significant weight loss outcomes in clinical trials

Fate mapping analysis reveals that adult microglia derive from primitive macrophages

Aim for 2030 grams of protein at breakfast

Additional UK SmPC warnings include diabetic retinopathy complications (particularly with rapid HbA1c improvement), gallbladder disease, and risk of dehydration leading to acute kidney injury