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Keywords GLP-1 Agonists SGLT-2 Inhibitors Diabetes Mellitus Chronic Kidney Disease Liver Transplantation Introduction Despite the life-saving intervention of liver transplantation for patients with ESLD (end-stage liver disease), the success of transplantation is compromised often by post-transplant complications, particularly diabetes mellitus and chronic kidney disease (CKD)

This change mirrors a growing preference for pharmacological solutions over invasive procedures

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T2DM is often viewed as a chronic lifelong medical condition that requires long-term maintenance therapy

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No dose adjustment is required for renal or hepatic impairment, though caution is advised in severe disease