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Effective July 1, 2025, AOM tirzepatide (sold as Zepbound) was removed from its standard preferred formulary ( 9 )

5 MMP = mitochondrial membrane potential 6 ROS = Reactive Oxygen Species

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It can be found that compared with the Model group, the Low group and High group secreted more insulin after berberine treatment (Figure 1I), and calculated homeostatic model assessment of insulin resistance (HOMA-IR) index according to the following formula: HOMA-IR = FBG (mM) Fasting insulin (mU/L)/22.5 (Figure 1J)
