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Description
A 2014 FDA and European Medicines Agency (EMA) joint analysis found similar rates of pancreatic cancer between GLP-1-treated patients and comparators, though absolute event numbers were small

Hagenaars SP, Coleman JRI, Choi SW, Gaspar H, Adams MJ, Howard DM, et al

Twice-daily formulations such as immediate-release exenatide (Byetta) have more specific timing requirements

Best Practices to Reduce Risk of Aspiration During Sedation/Anaesthesia To decrease gastric volume prior to sedation, thereby reducing the risk of aspiration, patients taking GLP-1 agonists either require doses of their medication to be held or to fast for longer periods than the current nil per os (NPO) guidelines

Heiss, C

Additional studies have also shown that patients taking GLP-1 receptor agonists also have significantly lower rates of kidney outcomes such as macroalbuminuria or progression to end-stage kidney disease
