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In a study on cultured human aortic endothelial cells (HAECs), stimulated by TNF- and LPS, liraglutide reduced monocyte adhesion to endothelial cells by reducing expression of VCAM-1 and E-selectin

The largest meta-analysis to date, comprising 13 cardiovascular outcome trials involving 83,258 patients with and without diabetes, confirmed that GLP-1 Ras significantly reduced major adverse cardiovascular events (MACEs), all-cause mortality, cardiovascular mortality, fatal and non-fatal strokes, coronary revascularization, and composite kidney outcomes [87]

doi: 10.1152/ajpendo.00330.2023 [DOI] [PMC free article] [PubMed] [Google Scholar] 170

The differential impact of three different NAD(+) boosters on circulatory NAD and microbial metabolism in humans

GrowthHormone Research Society workshop summary: consensus guidelines for recombinant human growth hormone therapy in Prader-Willi syndrome