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TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action

In this study, exogenous lactate markedly increased intracellular lactate level, and activated NLRP3 inflammasome in fibroblasts

Some research suggests these drugs can influence macrophage polarisation, shifting immune cells towards a less inflammatory phenotype

Glucagon-like peptide-1 : the basis of a new class of treatment for type 2 diabetes

Nonetheless, there are reasons to be optimistic about the roles GLP-1s may play in breast cancer prevention, treatment, and survivorship
