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Yes Zepbound alcohol diarrhea is most common in the 72-hour window after an injection

A generic version of Saxenda launched in August 2025, the first FDA-approved generic GLP-1 indicated for weight loss

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And emerging data suggest that optimizing the hormonal environment during the menopausal transition more broadly may positively influence weight loss trajectories and body composition outcomes during GLP-1 treatment [17], consistent with the mechanistic picture of restored hormonal signaling creating a more metabolically receptive physiological state

But if you crank somebody up really high, we dont know, but I speculate we would still get that resistance that I spoke up with insulin resistance