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BMJ 29:372:n71
doi: 10.1056/NEJMra043430
In humanized GLP-1-receptor mice, orally administered LY3502970 lowered glucose to a degree comparable with injected exenatide, demonstrating that a small molecule can reproduce a peptide agonists core metabolic action in an appropriate in-vivo model despite its partial-agonist classification
This weekly dosing schedule offers a streamlined and convenient option for patients, removing the need for daily injections while maintaining consistent therapeutic benefits
