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Meglutide participates in the activity of the appetite regulation center

When urinary changes do occur, they are more likely related to indirect factors associated with the medication's primary effects rather than a direct pharmacological action on the urinary system

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Pre-existing conditions also influence eligibility and monitoring needs

Based on the above evidence, we reasonably speculate that GLP-1R-based agonists have potential preventive or even therapeutic effects on MASLD, probably by improving insulin resistance and lipid metabolic disorders