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Though intuitively, people should prefer a pill over an injection, in my experience, patients are willing to take the weekly injection if it provides more robust weight and A1C lowering outcomes, says Tan

If ibuprofen or another NSAID is necessary, several strategies can minimize risk: Use the lowest effective dose for the shortest duration possible for example, 200400 mg of ibuprofen every 46 hours as needed, not exceeding 1,200 mg per day for over-the-counter use unless directed by a healthcare provider Take NSAIDs with food to reduce direct gastric irritation, though this does not eliminate ulcer risk Consider gastroprotection with a proton pump inhibitor (omeprazole, pantoprazole) if NSAID use will be prolonged or if risk factors for GI bleeding are present Maintain adequate hydration to protect kidney function, particularly if experiencing semaglutide-related nausea or vomiting For patients taking Rybelsus (oral semaglutide), remember to take it on an empty stomach with no more than 4 ounces of water, then wait at least 30 minutes before taking ibuprofen or other medications

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Close monitoring over time Regular followup visits to track weight, body composition, labs, blood pressure, and side effects

Our clients have reported not only significant weight loss but also improvements in their overall health, increased energy levels, and a boost in self-confidence

Since GLP-1s reduce blood sugar, even a few-point reduction is enough for the body to register as a change