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Investigations continue to examine how amylin signaling contributes to: Energy balance Nutrient sensing Gastrointestinal signaling Hormonal communication networks Metabolic regulation Studies continue to explore how amylin receptor activation influences physiological responses across multiple organ systems

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Increased body fat in individuals with obesity is associated with greater leptin secretion, which regulates hunger and energy balance [232]

These are expected GLP-1 side effects related to the mechanism of action

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