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Swelling in legs, ankles, or feet (peripheral edema) combined with weight gain can indicate heart failure, kidney dysfunction, or venous insufficiency
10.1016/S0140-6736(22)02033-5 [DOI] [PubMed] [Google Scholar] 13.Jastreboff, A

Fertil Steril 2018

About two thirds in each study arm had type 2 diabetes, about 60% had stage 3 fibrosis, almost half were taking a statin, and about 15% took a GLP-1 receptor agonist for diabetes or obesity

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Reaven et al
