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Younger users and men are especially prone to quitting, raising concerns since discontinuation often leads to weight regain.

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Retatrutide is a novel synthetic peptide designed as a triple agonist, targeting GLP-1, GIP, and glucagon receptors

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Once mechanical obstruction is excluded, gastric scintigraphy remains the gold standard for diagnosis although wireless motility capsule and breath testing are alternative methods for diagnosis

Preclinical and observational data suggested possible benefits, spurring rigorous clinical testing