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Helmstdter J, Frenis K, Filippou K, Grill A, Dib M, Kalinovic S, Pawelke F, Kus K, Krller-Schn S, Oelze M, Chlopicki S, Schuppan D, Wenzel P, Ruf W, Drucker DJ, Mnzel T, Daiber A, Steven S

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Alternatives include Wegovy, Zepbound, Mounjaro, Foundayo, Saxenda, and other GLP-1 medications

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A second mechanism of PKA-independent incretin potentiation of glucose-stimulated insulin secretion (GSIS) involves cAMP-regulated guanine nucleotide exchange factor (cAMP-GEF) EPAC2

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