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[17] [18] This suggests that the medication's metabolic effects remain active even when weight loss plateaus, providing continued cardiometabolic benefit beyond weight reduction alone

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The gut microbes in the third pathway can metabolize tryptophan into several molecules, such as indole and other derivatives compounds, with some of them acting as ligands to bind the aryl hydrocarbon receptor (AhR) (Williams et al., 2014

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