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Antidiabetogenic effect of glucagon-like peptide-1 (736)amide in normal subjects and patients with diabetes mellitus

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Statistical comparisons were performed using one-way ANOVA followed by Tukeys post hoc test

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Dose escalation schedule Both medications follow a gradual dose escalation to minimize side effects: Semaglutide: Starting at 0.25mg weekly, increasing every 4 weeks through 0.5mg 1.0mg 1.7mg the maintenance dose of 2.4mg weekly
