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Skipping meals and becoming dehydrated should also be avoided, as tirzepatide can affect blood sugar regulation and hydration levels

CD38-NAD(+)axis regulates immunotherapeutic anti-tumor T cell response

The mechanism of actionparticularly delayed gastric emptying and effects on gut motilityraises important considerations for those with inflammatory bowel disease

The proposed mechanism is fascinating
White fish is one of the gentlest proteins for sensitive stomachs

NICE first recommended the drug in draft guidance 2022, after a clinical trial of just under 2000 volunteers found that people lost on average 12% more weight with semaglutide alongside supervised weight loss coaching (BMJ 2023;380:556)
