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Acknowledgements This work was supported by research grants from the National Key Research and Development Program of China (2016YFA0100501), the Chinese National 973 Program (2012CB517502), the National Natural Sciences Foundation of China (81400798, 81400767, 81401142, 81270858, and 81570692), and the Beijing Natural Sciences Foundation of China (7163233)

Dulaglutide (Brand name: Trulicity) Administered as a weekly injection, primarily for diabetes

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The adults segment dominated the GLP-1 targeted peptide weight loss drugs market in 2024 because obesity prevalence is highest among adults, making them the primary target population for these therapies

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Common gastrointestinal side effects include nausea, vomiting, diarrhea, reflux, and constipation
