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SCFAs strongly stimulate PYY production in human enteroendocrine cells

Survodutide is now in Phase 3, so larger and longer data are coming

Medicines that mimic or enhance these hormones have become increasingly important in managing type 2 diabetes and, more recently, obesity

Researchers hypothesize that the difference may be due to variations in environmental exposure, genetics, or a combination

Orforglipron Versus Semaglutide Researchers enrolled nearly 1,700 adults with Type 2 diabetes inadequately controlled with metformin and HbA1c levels between 53 and 91 mmol/mol

Some GLP-1s also have strong evidence for cardiovascular benefit in certain patients, which is a big deal because heart disease risk is so tied up with diabetes