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Potential Side Effects of GLP-1 Medications: Gastrointestinal discomfort including constipation, diarrhea, nausea, and indigestion Loss of bone density and/or strength, loss of muscle mass and energy Inadequate nutrition intake from foods Key Considerations for GLP-1 Therapy Support: Ensure adequate Calcium, Magnesium, Vitamin K, and Vitamin D intake to maintain strong and healthy bones.* Prevent muscle loss by adding Protein, Amino Acids and other exercise support supplements into your routine.* Low energy levels may occur during GLP-1 therapy

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For plots c, d, and e, point estimates are represented as circles, and horizontal bars indicate 95% confidence intervals

Participants maintained an average weight loss of approximately 15% at 104 weeks on continued semaglutide treatment

doi: 10.1016/j.cmet.2013.04.008 2 NauckMAMeierJJ

In individuals with PCOS , insulin resistance and excess weight can interfere with ovulation , making it difficult to conceive