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Baek, HM15211, a novel GLP-1/GIP/glucagon triple-receptor co-agonist significantly reduces liver fat and body weight in obese subjects with non-alcoholic fatty liver disease: a phase 1b/2a, multi-center, randomized, placebo-controlled trial, J

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Over time, this chronic immune attack results in a gradual loss of functional thyroid tissue, with the clinical course typically progressing from an initial euthyroid state to subclinical hypothyroidism and, in a subset of patients, overt hypothyroidism requiring lifelong thyroid hormone replacement [13,14]
