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Severe abdominal pain, particularly if it is persistent and located in the upper abdomen radiating to the back, requires urgent assessment to exclude pancreatitis, a rare but serious adverse effect of GLP-1 receptor agonists identified in the Wegovy SmPC

What raises concerns are some of the recent reports of serious ADRs associated with GLP-1RAs: (i) Pfizers disclosure of elevated aminotransferases in users of lotiglipron (a novel oral GLP-1RA) is indicative of hepatocellular injury [11]

doi: 10.1016/j.regpep.2004.06.020 50 MentleinRGallwitzBSchmidtWE

The consultation may take place in person or virtually through Skype or FaceTime

5.2.2 Understands impact of own values, beliefs and professional and personal biases on decision making

Therapies targeting the androgen axis (e.g