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[1] Because its multiple ion-channel and neurotransmitter actions dampen pathologic cortical excitability, topiramate received United States marketing clearance in 1996 for monotherapy or adjunctive control of partial-onset and primary generalized tonic-clonic seizures

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Notably, deformities were only documented in records starting in 2023, limiting the reconstruction of the chronology and progression of the clinical course

Overall, approximately half of all dogs and cats seen were classified as having class II obesity and, during controlled weight reduction, they lost weight more slowly and lost more lean tissue mass, than those with class I obesity

They also include some Hungryroot-brand items that emphasize healthy versions of kitchen classics (like the chickpea cookie dough or cashew-based Parmesan sauce), prepared proteins, and even ready-to-eat meals

Drug Testing Rules in Professional and Collegiate Sports Different sports organizations have different drug testing policies