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For this, the Patient Health Questionnaire-9 (PHQ-9) [100] could be used, which consists of 9 items

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Indeed, DPP-4 acts as a receptor or costimulatory protein in immunomodulatory signaling processes in various immune cells such as CD8 + and CD4 + T cells, B cells, and macrophages, and hydrolyzes different sites of chemokines and interleukins that are part of bone remodeling