allodynia from glp-1 Can Semaglutide Cause Allodynia? Nerve Pain Facts glp 1 and skin sensitivity

And a fair bit of the time they're right

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doi: 10.1016/S0140-6736(09)61375-1 90 LeanMEJCarraroRFinerNHartvigHLindegaardMLRssnerSet al

Given their antiinflammatory properties, there has been some speculation that GLP-1 medicines could impair host immune defenses, but current clinical evidence does not indicate an increased risk of infections or obesity-related cancer (94)

Minireview: signal bias, allosterism, and polymorphic variation at the GLP-1R: implications for drug discovery

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