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Even though no direct contraindication exists, patients should discuss cannabis use with a licensed provider to ensure symptom management aligns with their weight loss or metabolic goals.

A study published in the New England Journal of Medicine, showed an average of 12.5% weight loss and over half lost 20% of their body weight

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PET All participants were injected with a bolus (250 MBq) of [11C]Raclopride following the local standard protocols for [11C]Raclopride PET studies 21,23,45

Furthermore, the STEP trials demonstrated improvements in waist circumference, lipid profiles, blood pressure, and C-reactive protein, all of which are cardiometabolic risk factors (4448)

The composition according to any one of the preceding embodiments, wherein the composition comprises a buffer and/or isotonic agent
