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When a medical intervention that supports weight loss is removed, most people will regain weight . How Researchers Studied Weight Regain After GLP-1s To better understand what typically happens when someone stops taking a weight loss drug, researchers reviewed data from 37 studies that followed more than 9,300 adults after they stopped taking medication for overweight or obesity
(ISBN: 978-0-7817-6555-8) Magkos F et al (2016): Effects of moderate and subsequent progressive weight loss on metabolic function and adipose tissue biology in humans with obesity

This neurological shift allows many people to naturally adopt smaller meal sizes without the constant struggle that typical calorie restriction demands

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