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Specifically, GLP-1 RAs showed significantly reduced risks of progression to systolic heart failure (HR 0.60) and stroke (HR 0.75) compared to SGLT2 inhibitors

Inhibitors of DPP-4 participate in the pancreatic-endocrine-osseous axis by increasing endogenous GLP-1

A study found that stopping and restarting GLP-1s could make the drug less effective in weight loss.

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Obesity is a chronic disease associated with many complications
